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Vitamin B12 for Fibromyalgia

Dec 8, 2015
  • Medical Information
  • Traditional Medicine
Woman with pill in her hand

Dose It Up

Given the obvious benefit and even dire necessity of B12, how much is enough and how much is too much? Typically a dosage of 1,000 micrograms a month is what is prescribed for a somewhat healthy patient needing just a little boost in B12.

However, some doctors who specialize in the treatment of fibromyalgia are choosing to augment oral supplementation of B12 with injected doses, comparable to or higher than doses typically prescribed for patients suffering from a B12 deficiency. Patients self-administer the dose using the same kind of syringe a diabetic would use to inject insulin.

Research has also shown that much higher doses are even more beneficial than once thought.

North Carolina-based internal medicine specialists Charles Lapp and Paul Cheney, each specializing in treating chronic fatigue and fibromyalgia, began experimenting with high dose vitamin B12 therapy in the early 1990s.

Initially, they were intrigued by three studies reported in the New England Journal of Medicine, which revealed high dose B12 therapy had either cured or greatly improved the symptoms of patients suffering from chronic fatigue and fibromyalgia-like neurological symptoms.

Interestingly, the patients in these studies had normal B12 blood counts, which would suggest that on paper, they had enough B12 in their systems. What the research showed was at least half of them experienced significant improvement in all symptoms, and as many as 80 percent reported at least some improvement, at doses of between 1,000 micrograms to 5,000 micrograms of B12 injected three times a week.

These results were thrilling for the doctors and their patients, but were still a mystery as to how or why the B12 was helpful even though their B12 blood levels were normal at the onset, and remained normal even at higher doses. The speculation was that their patients might have a problem with B12 absorption and utilization at the cellular level. Ongoing research through the years has clarified this speculation.

What It All Means

In 1997, Swedish scientists described their study of 12 patients who fulfilled the diagnostic criteria for both chronic fatigue and fibromyalgia. Although the patients had normal levels of B12 in their blood, they had extremely low or non-detectable levels of B12 in their spinal fluid, and by inference, in their brains.

The low amounts of B12 in the spinal fluid correlated with the degree of fatigue experienced by the patient. The finding suggested at least some chronic fatigue and fibromyalgia patients fail to metabolize B12 properly.

A year after this research, further findings determined that not only did chronic fatigue and fibromyalgia patients lack B12 in their nervous system, they also had abnormally high levels of homocysteine, an amino acid-like substance that is normally regulated in the cells by B12.

Among other things, high levels of homocysteine have been linked to heart disease. Further results from this research by the Swedish scientists showed that the higher homocysteine levels in patients were typically three times higher than in healthy people — the higher the level, the greater the severity of fatigue.

They concluded that the absence of B12 in the nervous system and high homocysteine levels among chronic fatigue and fibromyalgia sufferers constitute "an underlying factor" in both diseases.

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Three-Dollar Bottle of Life

For me personally, these findings saved my life. After almost two years of testing, constant pain, chronic fatigue, weight loss and weakness, my doctor discovered all the effort we had gone through led us to a simple answer found in a small vial of B12.

For the cost of a little over $3, I began regaining a measure of my life back. I was instructed to take an injection three times a week and eventually once a week.

It is also suggested that patients take oral supplements of other vitamins, particularly B6 and folate, since excess B12 can potentially compete with other B vitamins in the cells and hinder absorption.

A Final Word

B12 deficiency is not the root cause of fibromyalgia, nor is taking more B12 the cure for the disease. Rather, the deficiency is a condition within or because of the illness.

Developing a regime of B12 intake has proven to bring positive and often life-changing results. While it won’t cure you, it will prevent further deterioration and will control your symptoms.

Think about those exposed nerves again like the electrical wire without the rubber. B12 becomes the protective coating and the conduit for the body’s energy to flow as it should. I can’t guarantee what it will do for you, but for me that little bottle saved my life!

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Starla Rich
Starla Rich is a freelance writer and blogger who is a strong voice for those struggling with health issues that diminish quality of life. She is also an advocate for those dealing with the trauma and devastation of domestic violence and abuse. Starla is founder of Encouragement Enterprises, an organization that was created for the purpose of "paying forward" encouragement and hope through various venues. Connect with Starla on Facebook or email her at ncourage138@gmail.com. See all of Starla's articles
More Articles by Starla
Resources
  • Livestrong.com (Vitamin B12 for Fibromyalgia)
  • Whole Health MD (A Common B Vitamin for Fibromyalgia and Fatigue)
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